MAATS1

CFAP91
Identifiers
Aliases	CFAP91, AAT1, AAT1alpha, C3orf15, CaM-IP2, SPATA26, MYCBP associated and testis expressed 1, MAATS1, cilia and flagella associated protein 91, SPGF51
External IDs	OMIM: 609910; MGI: 2443598; HomoloGene: 33470; GeneCards: CFAP91; OMA:CFAP91 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	119,767,102 bp
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)
End	38,162,505 bp
RNA expression pattern
	Top expressed in
	right uterine tube; ; bronchial epithelial cell; ; pituitary gland; ; left testis; ; anterior pituitary; ; right testis; ; mucosa of paranasal sinus; ; sperm; ; body of pancreas; ; caput epididymis;
	Top expressed in
	choroidal fissure; ; utricle; ; spermatid; ; seminiferous tubule; ; spermatocyte; ; choroid plexus of fourth ventricle; ; olfactory epithelium; ; Epithelium of choroid plexus; ; lumbar subsegment of spinal cord; ; embryo;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding;
Cellular component	cytoplasm; mitochondrion; radial spoke stalk; axoneme; motile cilium; cytoskeleton; cell projection;
Biological process	cilium movement;
	Sources:Amigo / QuickGO
Orthologs
	89876
	320214
	ENSG00000183833
	ENSMUSG00000022805
	Q7Z4T9
	Q8BRC6
	NM_033364; NM_001320316; NM_001320317; NM_001320318
	NM_001081025; NM_177104
	NP_001307245; NP_001307246; NP_001307247; NP_203528
	NP_001074494
	Wikidata
View/Edit Human	View/Edit Mouse

AMY-1-associating protein expressed in testis 1 is a protein that in humans is encoded by the MAATS1 (formerly known as C3orf15) gene.^[5]^[6]^[7]

Interactions

C3orf15 has been shown to interact with MYCBP^[5] and AKAP1.^[5]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000183833 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000022805 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ ^a ^b ^c Yukitake H, Furusawa M, Taira T, Iguchi-Ariga SM, Ariga H (Nov 2002). "AAT-1, a novel testis-specific AMY-1-binding protein, forms a quaternary complex with AMY-1, A-kinase anchor protein 84, and a regulatory subunit of cAMP-dependent protein kinase and is phosphorylated by its kinase". J Biol Chem. 277 (47): 45480–92. doi:10.1074/jbc.M206201200. PMID 12223483.
^ Hayes VM, Gardiner-Garden M (Oct 2003). "Are polymorphic markers within the alpha-1-antitrypsin gene associated with risk of human immunodeficiency virus disease?". J Infect Dis. 188 (8): 1205–8. doi:10.1086/378641. PMID 14551891.
^ "Entrez Gene: C3orf15 chromosome 3 open reading frame 15".

External links

Human MAATS1 genome location and MAATS1 gene details page in the UCSC Genome Browser.

Matsuda E, Ishizaki R, Taira T, et al. (2005). "Structure and characterization of AAT-1 isoforms" (PDF). Biol. Pharm. Bull. 28 (5): 898–901. doi:10.1248/bpb.28.898. PMID 15863901.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Talmud PJ, Martin S, Steiner G, et al. (2004). "Progression of atherosclerosis is associated with variation in the alpha1-antitrypsin gene". Arterioscler. Thromb. Vasc. Biol. 23 (4): 644–9. doi:10.1161/01.ATV.0000065196.61663.8D. PMID 12692006.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Mashiba S, Wada Y, Takeya M, et al. (2001). "In vivo complex formation of oxidized alpha(1)-antitrypsin and LDL". Arterioscler. Thromb. Vasc. Biol. 21 (11): 1801–8. doi:10.1161/hq1101.098232. PMID 11701469.
Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.

This article on a gene on human chromosome 3 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000183833 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000022805 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid12223483-5] Yukitake H, Furusawa M, Taira T, Iguchi-Ariga SM, Ariga H (Nov 2002). "AAT-1, a novel testis-specific AMY-1-binding protein, forms a quaternary complex with AMY-1, A-kinase anchor protein 84, and a regulatory subunit of cAMP-dependent protein kinase and is phosphorylated by its kinase". J Biol Chem. 277 (47): 45480–92. doi:10.1074/jbc.M206201200. PMID 12223483.

[pmid14551891-6] Hayes VM, Gardiner-Garden M (Oct 2003). "Are polymorphic markers within the alpha-1-antitrypsin gene associated with risk of human immunodeficiency virus disease?". J Infect Dis. 188 (8): 1205–8. doi:10.1086/378641. PMID 14551891.

[entrez-7] "Entrez Gene: C3orf15 chromosome 3 open reading frame 15".

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Interactions

References

External links

Further reading