RTRAF

RTRAF
Identifiers
Aliases	RTRAF, CGI99, CLE, CLE7, LCRP369, RLLM1, CGI-99, C14orf166, hCLE1, chromosome 14 open reading frame 166, RNA transcription, translation and transport factor, hCLE
External IDs	OMIM: 610858; MGI: 1915295; HomoloGene: 9355; GeneCards: RTRAF; OMA:RTRAF - orthologs
Gene location (Human)
Chr.	Chromosome 14 (human)
End	52,010,694 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	19,873,892 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; gonad; ; right testis; ; left testis; ; cartilage tissue; ; ganglionic eminence; ; Achilles tendon; ; palpebral conjunctiva; ; right ventricle; ; body of pancreas;
	Top expressed in
	fossa; ; condyle; ; medial ganglionic eminence; ; endothelial cell of lymphatic vessel; ; trigeminal ganglion; ; primitive streak; ; renal corpuscle; ; vestibular sensory epithelium; ; medullary collecting duct; ; vas deferens;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	RNA polymerase II complex binding; identical protein binding; RNA binding; protein binding;
Cellular component	cytoskeleton; cytosol; nucleus; tRNA-splicing ligase complex; cytoplasm; microtubule organizing center; nucleoplasm; centrosome; perinuclear region of cytoplasm; mitotic spindle;
Biological process	RNA transport; regulation of transcription, DNA-templated; positive regulation of transcription by RNA polymerase II; transcription, DNA-templated; viral process; tRNA splicing, via endonucleolytic cleavage and ligation; negative regulation of protein kinase activity;
	Sources:Amigo / QuickGO
Orthologs
	51637
	68045
	ENSG00000087302
	ENSMUSG00000021807
	Q9Y224
	Q9CQE8
	NM_016039
	NM_026528
	NP_057123
	NP_080804
	Wikidata
View/Edit Human	View/Edit Mouse

RNA transcription, translation and transport factor is a protein that in humans is encoded by the RTRAF gene.^[5]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000087302 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000021807 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W (Aug 2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics". Genome Res. 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC 310876. PMID 10810093.
^ "RTRAF RNA transcription, translation and transport factor [ Homo sapiens (human) ]". Retrieved 2019-04-28.

Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. Bibcode:2005Natur.433...77A. doi:10.1038/nature03207. PMID 15635413. S2CID 4344740.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Howng SL, Hsu HC, Cheng TS, et al. (2004). "A novel ninein-interaction protein, CGI-99, blocks ninein phosphorylation by GSK3beta and is highly expressed in brain tumors". FEBS Lett. 566 (1–3): 162–8. doi:10.1016/j.febslet.2004.04.024. PMID 15147888.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Huarte M, Sanz-Ezquerro JJ, Roncal F, et al. (2001). "PA subunit from influenza virus polymerase complex interacts with a cellular protein with homology to a family of transcriptional activators". J. Virol. 75 (18): 8597–604. doi:10.1128/JVI.75.18.8597-8604.2001. PMC 115105. PMID 11507205.
Dawson SJ, White LA (1992). "Treatment of Haemophilus aphrophilus endocarditis with ciprofloxacin". J. Infect. 24 (3): 317–20. doi:10.1016/S0163-4453(05)80037-4. PMID 1602151.

This article on a gene on human chromosome 14 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000087302 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000021807 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10810093-5] Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W (Aug 2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics". Genome Res. 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC 310876. PMID 10810093.

[entrez-6] "RTRAF RNA transcription, translation and transport factor [ Homo sapiens (human) ]". Retrieved 2019-04-28.

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References

Further reading