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BAIAP3

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BAIAP3
Identifiers
AliasesBAIAP3, BAP3, BAI1 associated protein 3
External IDsOMIM: 604009; MGI: 2685783; HomoloGene: 20844; GeneCards: BAIAP3; OMA:BAIAP3 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001163270

RefSeq (protein)

n/a

Location (UCSC)Chr 16: 1.33 – 1.35 MbChr 17: 25.46 – 25.48 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

BAI1-associated protein 3 is a protein that in humans is encoded by the BAIAP3 gene.[5][6]

BAIAP3 was identified as a protein-binding partner of BAI1. BAI1 is a p53-target gene that encodes a brain-specific angiogenesis inhibitor. The protein is a seven-span transmembrane protein and a member of the secretin receptor family. BAIAP3 interacts with the cytoplasmic region of brain-specific angiogenesis inhibitor 1. BAIAP3 also contains two C2 domains, which are often found in proteins involved in signal transduction or membrane trafficking. Its expression pattern and similarity to other proteins suggest that it may be involved in synaptic functions.[6]

Interactions

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BAIAP3 has been shown to interact with Brain-specific angiogenesis inhibitor 1.[5]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000007516Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000047507Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b Shiratsuchi T, Oda K, Nishimori H, Suzuki M, Takahashi E, Tokino T, Nakamura Y (Nov 1998). "Cloning and characterization of BAP3 (BAI-associated protein 3), a C2 domain-containing protein that interacts with BAI1". Biochem Biophys Res Commun. 251 (1): 158–65. doi:10.1006/bbrc.1998.9408. PMID 9790924.
  6. ^ a b "Entrez Gene: BAIAP3 BAI1-associated protein 3".
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Further reading

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