Triamcinolone hexacetonide

Triamcinolone hexacetonide
Clinical data
Trade names	Aristospan
Other names	Triamcinolone acetonide 21-tebutate; Triamcinolone acetonide 21-(tert-butylacetate); 9α-Fluoro-11β,16α,17α,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with acetone, 21-(3,3-dimethylbutyrate); 9α-Fluoro-11β-hydroxy-16α,17α-((1-methylethylidene)bis(oxy))pregna-1,4-diene-3,20-dione 21-(3,3-dimethylbutyrate)
Drug class	Corticosteroid; Glucocorticoid
Legal status
Legal status	CA: ℞-only;
Identifiers
	IUPAC name 2-[(4aS,4bR,5S,6aS,6bS,9aR,10aS,10bS)-4b-Fluoro-5-hydroxy-4a,6a,8,8-tetramethyl-2-oxo-2,4a,4b,5,6,6a,9a,10,10a,10b,11,12-dodecahydro-6bH-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-6b-yl]-2-oxoethyl 3,3-dimethylbutanoate;
CAS Number	5611-51-8;
PubChem CID	21826;
ChemSpider	20516;
UNII	I7GT1U99Y9;
ChEBI	CHEBI:9670;
ChEMBL	ChEMBL1200878;
CompTox Dashboard (EPA)	DTXSID0048634 ;
ECHA InfoCard	100.024.575
Chemical and physical data
Formula	C30H41FO7
Molar mass	532.649 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C[C@]12C[C@@H]([C@]3([C@H]([C@@H]1C[C@@H]4[C@]2(OC(O4)(C)C)C(=O)COC(=O)CC(C)(C)C)CCC5=CC(=O)C=C[C@@]53C)F)O;
	InChI InChI=1S/C30H41FO7/c1-25(2,3)15-24(35)36-16-22(34)30-23(37-26(4,5)38-30)13-20-19-9-8-17-12-18(32)10-11-27(17,6)29(19,31)21(33)14-28(20,30)7/h10-12,19-21,23,33H,8-9,13-16H2,1-7H3/t19-,20-,21-,23+,27-,28-,29-,30+/m0/s1; Key:TZIZWYVVGLXXFV-FLRHRWPCSA-N;

Triamcinolone hexacetonide (brand name Aristospan; also known as triamcinolone acetonide 21-tebutate) is a synthetic glucocorticoid corticosteroid.^[3]^[4]^[5]

References

^ "Arthritis". Health Canada. 8 May 2018. Retrieved 13 April 2024.
^ "Regulatory Decision Summary for Triamcinolone Hexacetonide Injectable Suspension". Drug and Health Products Portal. 12 December 2017. Retrieved 13 April 2024.
^ Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 1228–. ISBN 978-1-4757-2085-3.
^ Index Nominum 2000: International Drug Directory. Taylor & Francis. 2000. p. 1657. ISBN 978-3-88763-075-1.
^ Morton IK, Hall JM (6 December 2012). Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Science & Business Media. pp. 280–. ISBN 978-94-011-4439-1.
^ World Health Organization (2023). The selection and use of essential medicines 2023: web annex A: World Health Organization model list of essential medicines: 23rd list (2023). Geneva: World Health Organization. hdl:10665/371090. WHO/MHP/HPS/EML/2023.02.

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