3-Hydroxykynurenine

3-Hydroxykynurenine
Names
	IUPAC name 2-Amino-4-(2-amino-3-hydroxyphenyl)-4-oxobutanoic acid
Identifiers
CAS Number	484-78-6 ;
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:1547 ;
ChEMBL	ChEMBL442576 ;
ChemSpider	87 ;
KEGG	C02794 ;
MeSH	3-hydroxykynurenine
PubChem CID	89;
UNII	27723548JL ;
CompTox Dashboard (EPA)	DTXSID00862009 ;
	InChI InChI=1S/C10H12N2O4/c11-6(10(15)16)4-8(14)5-2-1-3-7(13)9(5)12/h1-3,6,13H,4,11-12H2,(H,15,16) Key: VCKPUUFAIGNJHC-UHFFFAOYSA-N ; InChI=1/C10H12N2O4/c11-6(10(15)16)4-8(14)5-2-1-3-7(13)9(5)12/h1-3,6,13H,4,11-12H2,(H,15,16) Key: VCKPUUFAIGNJHC-UHFFFAOYAF;
	SMILES O=C(O)C(N)CC(=O)c1cccc(O)c1N;
Properties
Chemical formula	C10H12N2O4
Molar mass	224.21 g/mol
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

3-Hydroxykynurenine is a metabolite of tryptophan, which filters UV light in the human lens.^[1] It is one of two pigments identified as responsible for the goldenrod crab spider's (Misumena vatia) yellow coloration.

References

^ Malina, HZ; Martin, XD (1995). "Deamination of 3-hydroxykynurenine in bovine lenses: a possible mechanism of cataract formation in general". Graefes Arch Clin Exp Ophthalmol. 233 (1): 38–44. doi:10.1007/bf00177784. PMID 7721122. S2CID 25414197.
^ Schwarcz, Robert; John P. Bruno; Paul J. Muchowski; Hui-Qiu Wu (July 2012). "Kynurenines in the Mammalian Brain: When Physiology Meets Pathology". Nature Reviews Neuroscience. 13 (7): 465–477. doi:10.1038/nrn3257. PMC 3681811. PMID 22678511.

References

See also