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2-Phospho-L-lactate guanylyltransferase

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2-Phospho-L-lactate guanylyltransferase
Identifiers
EC no.2.7.7.68
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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NCBIproteins

2-Phospho-L-lactate guanylyltransferase (EC 2.7.7.68, CofC, MJ0887) is an enzyme with systematic name GTP:2-phospho-L-lactate guanylyltransferase.[1] This enzyme catalyses the following chemical reaction

(2S)-2-phospholactate + GTP (2S)-lactyl-2-diphospho-5'-guanosine + diphosphate

This enzyme is involved in the biosynthesis of coenzyme F420.

References

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  1. ^ Grochowski LL, Xu H, White RH (March 2008). "Identification and characterization of the 2-phospho-L-lactate guanylyltransferase involved in coenzyme F420 biosynthesis". Biochemistry. 47 (9): 3033–7. doi:10.1021/bi702475t. PMID 18260642.
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